教师风采

罗成

来源:yxy发稿时间:2016-06-14浏览次数:354

 

 

 

罗成:男,1983年7月生,博士研究生学历,博士学位,生物化学与分子生物学专业,讲师。

教学情况:

(1)近五年来开设主讲的主要课程有:生物化学、医学生物化学、细胞生物学。

(2)共同主持2016年宜春学院大学生能力建设项目1项(2016年江西省大学生生物化学与分子生物学实验技能与创新设计大赛)。

科研情况:

(1)研究方向:天然化合物干预疾病、纳米材料生物安全性评价以及纳米药物递送系统研发。

(2)获奖及社会兼职:曾获线粒体生物医学国际研讨会暨中国线粒体2011学术会议“Zeiss 青年研究者奖”,教育部博士研究生学术新人奖等,兼任宜春学院药学专业硕士生导师、江西省生物化学与分子生物学学会第8届理事会理事、国际期刊nanomedicine,oncotarget,Tissue and Cell等杂志审稿人。

(3)科研课题:2015年主持在研1项江西省教育厅科学技术研究项目(磁性纳米颗粒对病理或应激状态下机体的影响研究),参与在研国家自然科学基金地区基金1项(TREK-1-BDNF-mTOR 通路介导丁基苯酞快速抗抑郁的分子机制研究,第3参与人),参与在研2项江西省教育厅科学技术研究项目(热休克蛋白HSP70在介孔二氧化硅纳米粒致肾毒性中的作用,高载药量姜黄素-白蛋白纳米颗粒的制备及细胞效应研究,均为第2参与人),参与完成国家自然科学基金青年基金项目2项(羟基酪醇对孕期应激引起的子代认知功能障碍的预防和保护作用,Ⅱ型脂肪酸合成酶抑制剂对糖尿病状况下线粒体功能的影响,均为第2参与人);2013年参与完成国家自然科学基金面上项目1项(胰岛素抵抗中的线粒体自噬调节机制,第3参与人)。

(4)学术论文发表及专著出版:共发表论文28篇,其中发表SCI论文23篇(第一作者10篇),中文核心期刊论文5篇(全为第一作者),参编专著1部,列表如下:

专著:

参编由刘健康,王学敏主编的《线粒体医学与健康》一书的第6章---“线粒体研究的基本实验方法”,该书由科学出版社2012年8月第一版发行。ISBN 978-7-03-035258-3。

学术论文:

[1] 罗成,李艳,龙启文,龙建纲,纳米酶在葡萄糖分析检测中的应用研究进展,中国生物医学工程学报,2016,35(1):105-113.

[2]  Liang Yang(共同一作), Cheng Luo(共同一作), Cong Chen, Xun Wang, Wen Shi, Jiankang Liu. All-trans retinoic acid protects against doxorubicin-induced cardiotoxicity by activating the ERK2 signalling pathway, British Journal of Pharmacology, 2016, 173(2): 357-371. (SCI影响因子:4.842)

[3] 罗成,李艳,龙建纲,四氧化三铁纳米颗粒过氧化物酶样活性的应用,科学通报,2015,60(35):3478-3488.

[4] 罗成,李艳,龙建纲,纳米材料模拟酶的应用研究进展,中国科学:化学,2015,45(10):1026-1041.

[5]  Cheng Luo, Yan Li, Liang Yang, Xun Wang, Jiangang Long, Jiankang Liu. Superparamagnetic iron oxide nanoparticles exacerbate the risks of reactive oxygen species-mediated external stresses, Archives of Toxicology, 2015, 89(3): 357-369. (SCI影响因子:5.98)[6]  Cheng Luo, Yan Li, Bo Zhou, Liang Yang, Hua Li, Zhihui Feng, Yuan Li, Jiangang Long, Jiankang Liu. A monocarbonyl analogue of curcumin, 1,5-bis(3-hydroxyphenyl)-1,4-pentadiene-3-one (Ca 37), exhibits potent growth suppressive activity and enhances the inhibitory effect of curcumin on human prostate cancer cells, Apoptosis, 2014, 19(3): 542-553. (SCI影响因子:3.685)

[7]  罗成,刘健康,羟基酪醇抗肿瘤机制研究进展,中国科学:生命科学,2014,44(1):14-20.

[8]  Cheng Luo, Yan Li, Liang Yang, Yan Zheng, Jiangang Long, Jinjing Jia, Shengxiang Xiao, Jiankang Liu. Activation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts, International Journal of Nanomedicine, 2014, 9(1): 4763-4772. (SCI影响因子:4.383)

[9]  Cheng Luo, Hui Wang, Xiaoxiao Chen, Yang Cui, Hua Li, Jiangang Long, Xiaoyan Mo, Jiankang Liu. Protection of H9c2 rat cardiomyoblasts against oxidative insults by total paeony glucosides from Radix Paeoniae Rubrae, Phytomedicine, 2013, 21(1): 20-24. (SCI影响因子:3.126)

[10]  Cheng Luo, Yan Li, Liang Yang, Zhihui Feng, Yuan Li, Jiangang Long, Jiankang Liu. A cigarette component acrolein induces accelerated senescence in human diploid fibroblast IMR-90 cells, Biogerontology, 2013, 14(5): 503-511. (SCI影响因子:3.29)

[11]  Cheng Luo, Yan Li, Hui Wang, Yang Cui, Zhihui Feng, Hua Li, Yuan Li, Ying Wang, Karin Wurtz Peter Weber, Jiangang Long, Jiankang Liu. Hydroxytyrosol Promotes Superoxide Production and Defects in Autophagy Leading to Anti-proliferation and Apoptosis on Human Prostate Cancer Cells, Current Cancer Drug Targets, 2013, 13(6): 625-639. (SCI影响因子:3.522)

[12]  Cheng Luo, Yan Li, Hui Wang, Zhihui Feng, Yuan Li, Jiangang Long, Jiankang Liu. Mitochondrial accumulation under oxidative stress is due to defects in autophagy, Journal of Cellular Biochemistry, 2013, 114(1): 212-219. (SCI影响因子:3.263)

[13] 罗成,刘健康,羟基酪醇作为线粒体营养素的调控机制,生命科学,2012,24(10):1114-1120.

[14] Cheng Luo, Jiangang Long, Jiankang Liu. An improved spectrophotometric method for a more specific and accurate assay of mitochondrial complex III activity. Clinica Chimica Acta. 2008, 395(1-2): 38-41.(SCI影响因子:2.824)

[15]  Cheng Luo, Xuemin Wang, Jiangang Long, Jiankang Liu. An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates. Journal of Biochemical and Biophysical Methods. 2006, 68(2):101-11.(目前已改刊)

[16]  Lijuan Sun, Cheng Luo, Jiankang Liu. Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation, Food & Function, 2014, 5(8): 1909-1914. (SCI影响因子:2.791)

[17]  Lijuan Sun, Cheng Luo , Jiangang Long , Dongzhi Wei, Jiankang Liu. Acrolein is a mitochondrial toxin: Effects on respiratory function and enzyme activities in isolated rat liver mitochondria, Mitochondrion. 2006, 6(3):136-42. (SCI影响因子:3.249)

[18]  Yan Li, Youshen Wu, Cheng Luo, Bo Wang, Daocheng Wu. Rewritable magnetic fluorescence-encoded microspheres: preparation, characterization, and recycling, Journal of Materials Chemistry C, 2015, 3(31): 8262-8271. (SCI影响因子:4.696)

[19]  Yan Li, Youshen Wu, Cheng Luo, Feilong Yang, Lei Qin, Tao Fu, Guangquan Wei, Xiaowei Kang, Daocheng Wu. Preparation and characterization of narrow-dispersed magnetic colloidal nanoparticle cluster/silica microspheres with controlled sizes, high saturation magnetization and MRI enhancement effect, Journal of Materials Chemistry B, 2013, 1(36): 4644-4654. (SCI影响因子:4.726)

[20]  Jiangang Long, Jiangang Ma, Cheng Luo, Xiaoyan Mo, Lei Sun, Weijin Zang, Jiankang Liu. Comparison of two methods for assaying complex I activity in mitochondria isolated from rat liver, brain and heart, Life Sciences, 2009, 85(7-8):276-280. (SCI影响因子:2.702)

[21 ] Xuesen Li, Zhongbo Liu, Cheng Luo, Haiqun Jia, Lijuan Sun, Bei Hou, Weili Shen, Lester Packer, Carl W. Cotman, Jiankang Liu. Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction, Free Radical Biology and Medicine, 2008, 44(7):1465-1474. (SCI影响因子:5.736)

[22]  Lin Zhao, Xuan Zou, Zhihui Feng, Cheng Luo, Jing Liu, Hao Li, Liao Chang, Hui Wang, Yuan Li, Jiangang Long, Feng Gao, Jiankang Liu. Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats, Experimental Gerontology, 2014, 56: 3-12. (SCI影响因子:3.485)

[23]  Xiaoqing Cai, Haiqun Jia,  Zhongbo Liu, Bei Hou, Cheng Luo, Zhihui Feng, Wenxin Li, Jiankang Liu. Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative damage in an MPP(+) -induced cellular model of Parkinson's disease, Journal Of Neuroscience Research. 2008, 86(16):3622-34. (SCI影响因子:2.594)

[24]  Xiaoqing Cai, Jiejie Hao, Xiaoyong Zhang, Bozhang Yu, Jinming Ren, Cheng Luo, Qingnuan Li, Qing Huang, Xianglin Shi, Wenxin Li, Jiankang Liu. The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction, Toxicology and Applied Pharmacology, 2010, 243(1): 27-34. (SCI影响因子:3.705)

[25]  Jiejie Hao, Weili Shen, Chuan Tian, Zhongbo Liu, Jinmin Ren, Cheng Luo, Jiangang Long, Edward Sharman, Jiankang Liu. Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats, Journal of Cellular and Molecular Medicine, 2009, 13(4):701-11.(SCI影响因子:4.014)

[26]  Weili Shen, Jiejie Hao, Chuan Tian, Jinmin Ren, Lu Yang, Xuesen Li, Cheng Luo, Carl W. Cotma, Jiankang Liu. A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic goto–kakizaki rats, PLoS ONE, 2008, 3(6): e2328. (SCI影响因子:3.234)

[27]  Xuan Zou, Chunhong Yan, Yujie Shi, Ke Cao, Jie Xu, Xun Wang, Cong Chen, Cheng Luo, Yuan Li, Jing Gao, Wentao Pang, Jialong Zhao, Fei Zhao, Hao Li, Adi Zheng, Wenyan Sun, Jiangang Long, Ignatius Man-Yau Szeto, Youyou Zhao, Zhizhong Dong, Peifang Zhang, Junkuan Wang, Wuyuan Lu, Yong Zhang, Jiankang Liu, Zhihui Feng. Mitochondrial dysfunction in obesity associated non-alcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin, Antioxidants & Redox Signaling, 2014, 21(11): 1557-1570. (SCI影响因子:7.407)

[28]  Hongyu Zhang, Haiqun Jia, Jianghai Liu, Ni Ao, Bing Yan, Weili Shen, Xuemin Wang, Xin Li, Cheng Luo, Jiankang Liu. Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease, Journal of Cellular and Molecular Medicine, 2010, 14(1-2): 215-25.(SCI影响因子:4.014)